Valgancyclovir

Asia Bio-Pharmaceutical Research Institute

Valgancyclovir

Product name:Valgancyclovir
CAS: 175865-60-8
Molecular Formula: C14H22N6O5
Molecular Weight: 354.36
Product description:For acquired immune deficiency syndrome (AIDS) patients with cytomegalovirus (CMV) retinitis. ; Be more yesterday galloway pharmacology function: this product is a synthesis of 2 - deoxyguanosine analogue, disease-resistant poison is more yesterday (ganciclovir) respectively.there precursor drugs, can greatly reduce the toxicity of more yesterday galloway. Its pharmacodynamics characteristics the same as the more yesterday galloway. Oral printing more yesterday after respectively.there esterase in intestinal mucosa cells and liver esterase, rapidly hydrolyzed to more yesterday, respectively.there more yesterday in virus respectively.there 3 phosphoric acid and enzyme phosphorylation in cells generate more ever galloway, the latter with triphosphate deoxyguanosine (dGTP) competition as the substrate of the viral DNA polymerase, thus inhibiting viral DNA synthesis, resulting in a resistance activity of cytomegalovirus (CMV).

 

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