Tirofiban Hydrochloride

Asia Bio-Pharmaceutical Research Institute

Tirofiban Hydrochloride

Product name:Tirofiban Hydrochloride
CAS: 142373-60-2
Molecular Formula: C22H36N2O5S·HCl·H2O
Molecular Weight: 495.08
Product description:This product is a high efficient reversible confirmed to platelet surface glycoproteins (GP) Ⅱ b/Ⅲ a receptor antagonist. Fibrinogen and platelet GP Ⅱ b/Ⅲ a receptor is the final common pathway of platelet aggregation, platelet activation can induce the GP Ⅱ b/Ⅲ conformational changes a receptor, the receptor and the affinity of fibrinogen increased significantly, the combination of fibrinogen can make platelets occurs crosslinking, platelet aggregation. Therefore, regardless of the cause of thrombosis, the platelet activation, adhesion and accumulation is the key step in the process of arterial thrombosis, including GP Ⅱ b/Ⅲ a receptor in platelet aggregation and thrombosis plays an important role in the process. This product competitive inhibition fibrinogen and platelet GP Ⅱ b/Ⅲ a receptor combination, inhibit platelet aggregation, prolong the bleeding time, inhibit thrombosis.

 

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