Penciclovir

Asia Bio-Pharmaceutical Research Institute

Penciclovir

Product name:Penciclovir
CAS: 39809-25-1
Molecular Formula: C10H15N5O3
Molecular Weight: 253.26
Product description:In virus cells, the virus thymidine kinase deoxyuridine phosphorylation of this product into spray yesterday monophosphate, respectively.there cell kinase will spray smoothie monophosphate respectively.there into spray yesterday galloway triphosphate. In vitro experiments showed that the spray triphosphate respectively.there with solid guanine nucleoside triphosphate competitive inhibition of herpes simplex virus polymerase, and selective inhibition of herpes simplex virus DNA synthesis and inhibition. The product of herpes simplex virus resistant mutant strains is a result of virus thymidine kinase deoxyuridine or DNA polymerase properties are changed, the most common resistance to virus mutant strains of acyclovir lack of thymidine nucleoside kinase, they, this article also in drug resistance.
 

 

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