Latanoprost

Asia Bio-Pharmaceutical Research Institute

Latanoprost

Product name:Latanoprost
CAS: 130209-82-4
Molecular Formula: C26H40O5
Molecular Weight: 432.5928
Product description:This product is almost colorless light yellow viscous oil, the relative molecular mass is 432.58, the chemical formula for C26H40O5. It is an inactive substance until in corneal transfer into a product of the rear active enzymes.This product for free acid hydrolysis in the cornea, the free acid from corneal spread out and into the room, about 2 h can achieve peak blood. Intraocular pressure began to decline after 3 ~ 4 h, 8 ~ 12 h maximum drop, 24 h intraocular pressure not to rise. The drug in aqueous humor outflow is expelled, the half-life of about 2 h. By conjunctiva or mucous membrane produce systemic absorption, absorption of drug in blood circulation system, after hepatic metabolism mainly with urinary excretion.Primary open-angle glaucoma, and difficult to treat with other drugs or tolerance of the local treatment of patients with high intraocular pressure.
 

 

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