Fulvestrant

Asia Bio-Pharmaceutical Research Institute

Fulvestrant

Product name:Fulvestrant
CAS: 129453-61-8
Molecular Formula: C32H47F5O3S
Molecular Weight: 606.77
Product description:A steroid anti-estrogen drugs, its chemical structure is similar to estradiol, the difference is that it have connection at 7 alpha group; It is 17 beta estradiol alkyl amine analogues, can by occupying ER antagonism estrogen effect, and inhibit the estrogen stimulation gene activation, therefore, necessary to affect the cell cycle of estrogen related process; Its affinity with the ER is close to estrogen, is 100 times of tamoxifen. Cell apoptosis is vital to maintain homeostasis, at the same time it can also be fluorine d SiQun another major mechanism of therapeutic effect.
 

 

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