Product name:Chloroquine
CAS: 54-05-7
Molecular Formula: C18H26ClN3
Molecular Weight: 319.87
Product description:This product and other 4 - aminoquinoline antimalarial drugs (such as piperaquine, acetaminophen sinensis, etc.) mainly work on parasites within red period, was likely interfere with the parasite crack colonization of DNA replication and transcription process or hindered them swallowing function, so that the insect body died due to a lack of amino acids. This product can effectively control symptoms of malaria attacks. For infrared period without effect, prevent recurrence, but because of the role is durable, thus delayed recurrence (p. falciparum because there was no infrared period, so it can be cure). For primary infrared period is invalid, is have no direct effect on gametophyte, therefore cannot make etiology prevention, can interrupt transmission. At present there are quite a number of plasmodium falciparum clinical found this resistance, reduce the product efficacy, so in many cases need to switch to other antimalarial drug or drug combinations. This product after oral and intestinal absorption quickly and fully, only 8% of the droppings. 1 ~ 2 hours after taking the drug blood concentration peak namely, t1/2 to 48 hours. Can be stored in the tissue of the internal organs, can be in red.
Chloroquine
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