Brivudine

Asia Bio-Pharmaceutical Research Institute

Brivudine

Product name:Brivudine
CAS: 69304-47-8
Molecular Formula: C13H19Cl5N4
Molecular Weight: 408.5818
Product description:Are very similar to nucleoside substance, can inhibit the - varicella zoster virus (VZV) replication. VZV related strains of bromine, is also very sensitive. In infected cells, bromine, to undertake a series of phosphorylation, phosphoric acid in the cell by virus thymidine kinase catalytic conversion process, the final formation of bromine, three phosphates, it can inhibit the replication of the virus. This process is only in the virus infected cells, thus bromine, the antiviral effect of highly selective. Bromine, triphosphate formation, can exist within the cells is more than 10 hours, and with the effect of virus DNA polymerase, inhibiting virus replication.Indications in the normal immune function of early treatment of adult patients with acute herpes zoster.

 

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