Product name:Amoxapine
CAS: 14028-44-5
Molecular Formula: C17H16ClN3O
Molecular Weight: 313.7814
Product description:This product is a diphenyl and oxygen and nitrogen zhuo tricyclic antidepressants, compared with the c m lamictal, have similar antidepressant effect, but the work fast, low toxicity to the heart and choline and sedation weak resistance. This product can inhibit the reuptake of presynaptic membrane of NA in the brain (small impact on the reuptake of 5 - HT), have a strong spirit of antidepressant and excitation. Oral absorption quickly and completely, after the l - 2 hours of blood drug concentration peak, in the lungs, heart, kidney, brain, spleen tissues concentration is higher. In the organization concentration is 10 times higher than the plasma concentration. Hepatic metabolism of 7 - hydroxy amor and 8 hydroxy amoxapine, all have antidepressant activity, the t1/2 were 6.5 hours and 30 hours. Most of the metabolites with glucuronic acid, and finally from the kidneys, small since its droppings.