Sodium hyaluronate

Asia Bio-Pharmaceutical Research Institute

Sodium hyaluronate

Product name:Sodium hyaluronate
CAS:9067-32-7
Molecular Formula:C14H22NNaO11
Formula Weight:403.31
Specification:1g
Description:
Sodium hyaluronate is the sodium salt of hyaluronan. It is a visco-elastic polymer normally found in the aqueous and vitreous humour. Sodium Hyaluronate occurs naturally on the corneal endothelium, bound to specific receptors. Sodium hyaluronate has a high affinity for the receptors. Brand Names include: AMO Vitrax; Amvisic Plus; Cystistat; Healon; Hyalgan; Hylo-Comod (Eye Drop).
Sodium hyaluronate, also known as sodium hyaluronate, is a physiological active substance widely existing in human body. It is a kind of high molecular weight straight-chain mucopolysaccharide, which is made up of glucosuronic acid and acetamidohexose. A viscoelastic solution with physiological acidity and alkalinity and ionic strength is formed in water. Its molecular morphology can be changed, so the injection needle with a smaller size can also pass through. Sodium hyaluronate will not produce inflammatory substances extracted, known as Healon. When 10 mg of this product is dissolved in 1 ml saline, its viscosity can be 200,000 times higher than that of aqueous solution or saline. Healon's protein content is less than 0.5%, which is a sterile high purity solution.

Sodium hyaluronate belongs to non-drug neutral medium. Sodium hyaluronate injection is a colorless and clear viscous liquid. Sodium hyaluronate is the main component of joint synovial fluid and a component of cartilage matrix. It plays a lubricating role in joint cavity. It can reduce the friction between tissues and play its elastic role. It can buffer the effect of stress on articular cartilage and play its due physiological function. Sodium hyaluronate with high molecular weight, high concentration and high viscoelasticity in articular cavity can obviously improve the inflammatory reaction of joint, enhance the viscous and lubricating function of joint fluid, protect articular cartilage, promote the healing and regeneration of articular cartilage, alleviate pain and increase the range of motion of joint. The general dosage of sodium hyaluronate for joint is 1 ml (10 mg) for temporomandibular joint, 2 ml (20 mg) for shoulder joint and 2.5 ml (25 mg) for hip and knee joint. Mainly used for the treatment of degenerative osteoarthritis, chronic traumatic arthritis, rheumatoid or rheumatoid arthritis, temporomandibular arthritis, femoral head aseptic necrosis and so on.

 

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