Product name:Amphotericin B
CAS:1397-89-3
Molecular Formula:C47H73NO17
Formula Weight:924.08
Specification:1g
Description:
Amphotericin B (Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec) is a polyene antifungal drug, often used intravenously for systemic fungal infections. Two amphotericins, amphotericin A and amphotericin B are known, but only B is used clinically, because it is significantly more active in vivo. Amphotericin A is almost identical to amphotericin B (having a double C=C bond between the 27th and 28th carbon), but has little antifungal activity. Currently, the drug is available as plain amphotericin B, as a cholesteryl sulfate complex, as a lipid complex, and as a liposomal formulation. The latter formulations have been developed to improve tolerability for the patient, but may show considerably different pharmacokinetic characteristics compared to plain amphotericin B.