Product name:Rat Osteopontin,OPN ELISA Kit
Description:
Osteopontin (OPN), also known as early T lymphocyte activation 1 (Eta-1), is a secreted multifunctional glyco-phosphoprotein with roles in bone metabolism, immune regulation, tissue remodeling , cell survival, and tumor progression .OPN regulates macrophage differentiation and recruitment. It also functions as a chemotactic factor and co-stimulator of T cells and may act as a Th1 cytokine, stimulating IL-12 production. OPN production by macrophages is upregulated at sites of tissue remodeling including the placenta, endometrium and myocardium post-infarction. OPN is expressed by many tumor types and plays a role in tumor progression and metastasis. OPN may also be upregulated during autoimmune processes such as rheumatoid arthritis or in granulomatous lesions in response to infections such as tuberculosis.
Rat Osteopontin,OPN ELISA Kit
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