Human sEPCR ELISA Kit

Asia Bio-Pharmaceutical Research Institute

Human sEPCR ELISA Kit

Product name:Human sEPCR ELISA Kit
Description:
A soluble form of EPCR (sEPCR) has recently been detected in normal human plasma and has been shown to bind protein C and APC with an affinity similar to that of intact membrane-bound EPCR. In healthy individuals, sEPCR circulates at a concentration of 2.5 nM, a level that can increase up to 5-fold in patients with sepsis or systemic lupus erythematosus.Since EPCR interacts with the membrane-binding Gla domain of protein C, it is possible that binding to sEPCR and phospholipid is mutually exclusive. Alternatively, sEPCR could mask the factor Va-binding site on APC or alter the macromolecular substrate specificity of the enzyme by altering the conformation of the extended substrate binding pocket.

 

Send Enquiry Online

This form is unable to receive your inquiry from aol, hotmail, gmail or others but company email address.For more information OR other products. Please contact us by Email, Tel, Fax or Send online enquiry. We will reply you as soon as possible.

1. Email: sales@pharmaceutical-sales.net
2. Tel: +86 592 5365887
2. WhatsApp: +86 189 6516 2351