Human EPOR ELISA Kit

Asia Bio-Pharmaceutical Research Institute

Human EPOR ELISA Kit

Product name:Human EPOR ELISA Kit
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Erythropoietin receptor(EPOR) is a 66 kDa peptide and is a member of the cytokine receptor  superfamily that contains aW-S-X-W-S motif and four cysteine residues in the extracellar domain.  Erythropoietin (EPO) is the regulator of red blood cell formation. Its receptor (EPOR) is now  found in many cells and tissues of the body. EpoR is also shown to occur in tumor cells and Epo  enhances the proliferation of these cells through cell signaling. EPOR antagonist can reduce the  growth of the tumor in vivo. EpoR is expressed in high or low affinity forms, but the high- affinity receptor is likely the more physiologically relevant class. A peak in EpoR expression  occurs on erythroid progenitor cells at the CFU-E/proerythroblast stage, but subsequently  decreases following maturation and differentation; EpoR cannot be detected on reticulocytes.
 

 

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