Human E-Selectin ELISA Kit

Asia Bio-Pharmaceutical Research Institute

Human E-Selectin ELISA Kit

Product name:Human E-Selectin ELISA Kit
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CD62E is also known as endothelial leukocyte adhesion molecule 1 (ELAM1) or E selectin. It is a  type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L  and CD62P). Selectins are C type cell surface lectins that play a role in leukocyte adhesion to  the blood vessel wall endothelium. CD62E (E selectin) is an endothelial cell specific selectin  that is expressed on cytokine induced endothelial cells only after activation with proinflammatory  cytokines. In vitro experiments have shown that IL1, TNFalpha and bacterial wall components like  lipopolysaccharides induce the transcription of CD62E in an NFkB dependent signalling cascade.

 

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