Product name:Human Cyclic AMP response element binding protein,CREB ELISA Kit
Description:
CREB (cAMP response element-binding) proteins are transcription factors which bind to certain sequences called cAMP response elements (CRE) in DNA and thereby increase or decrease the transcription of certain genes.
CREB has many functions in many different organs although most of its functions have been studied in relation to the brain.CREB is also important for the survival of neurons, as shown in genetically engineered mice, where CREB and CREM were deleted in the brain.
In humans, abnormalities of a protein which interacts with the KID domain of CREB, the CREB binding protein (CBP) is associated with Rubinstein-Taybi syndrome.