Human CD30 ELISA Kit

Asia Bio-Pharmaceutical Research Institute

Human CD30 ELISA Kit

Product name:Human CD30 ELISA Kit
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CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally  identified as a cell surface antigen of Hodgkin's and Reed-Sternberg cells using monoclonal  antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates  pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell  death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+  lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its  expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's  lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B  cells after activation.

 

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