Product name:Human adaptor molecule apoptotic peptidase activating factor 1,APAF1 ELISA Kit
Description:
APAF1 binds to Cytochrome c (APAF2) and Caspase 9 (APAF3), which leads to Caspase 9 activation. Activated Caspase 9 in turn cleaves and activates Caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. APAF1 can also associate with Caspase 4 and Caspase 8. APAF1 transcript is ubiquitously expressed in human tissues.
Human adaptor molecule apoptotic peptidase activating factor 1,APAF1 ELISA Kit
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