Product name:Roxithromycin
CAS:80214-83-1
Molecular Formula:C41H76N2O15
Formula Weight:837.05
Specification:100g
Description:Roxithromycin is white crystalline powder, odorless and bitter. Soluble in ethanol or acetone, more soluble in methanol or ether, almost insoluble in water.
Roxithromycin is suitable for pharyngitis and tonsillitis caused by streptococcus pyogenes, sinusitis, otitis media, acute bronchitis, acute attack of chronic bronchitis caused by sensitive bacteria, pneumonia caused by mycoplasma pneumoniae or chlamydia pneumoniae; Infection of urinary and reproductive system caused by chlamydia trachomatis (urethritis and cervicitis); Infection of skin, soft tissue and other parts of the body caused by sensitive bacteria; It is also used for nonspecific and gonococcal genital infections. An infection caused by legionella bacteria. Pediatric infection.
Roxithromycin is characterized by acid resistance and good oral absorption, t1/2 is 12 to 14 hours, which is more than 6 times higher than erythromycin. Wide distribution in the body, in the upper and lower respiratory tract, reproductive tract and skin can reach a very high concentration and maintain a long time. Most of it is metabolized in the body.
Clinical application evaluation of Roxithromycin: the clinical and bacteriological cure rate of chlamydia urethritis and cervicitis is 93-97%, the curative effect of genital infection is similar to doxycycline, the cure rate of skin infection is more than 90%, the effective rate of treating respiratory tract infection is 83% and 50%, and the effective rate of pneumonia and dental infection is 79% and 85%.