Product name:Fibronectin
CAS:86088-83-7
Specification:1mg
Description:
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin and heparan sulfate proteoglycans (e.g. syndecans).
Fibronectin plays a major role in cell adhesion, growth, migration and differentiation, and it is important for processes such as wound healing and embryonic development.Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis.