D-Lactic dehydrogenase

Asia Bio-Pharmaceutical Research Institute

D-Lactic dehydrogenase

Product name:D-Lactic dehydrogenase
CAS:9028-36-8
Specification:5ku
Description:
D - Lactic dehydrogenase as the metal protein containing zinc ions, composed of two subunits H and M, anaerobic glycolysis is sugar and sugar dysplasia, one of the important enzymes can propionate catalyzed with reduction and oxidation reaction between L - Lactic acid, can also be a - keto acid catalysis. LDH is widely found in human tissues, with the highest content in kidney, followed by myocardium and osteomycin. LDH in erythrocytes is about 100 times of normal serum.

D - Lactic dehydrogenase have 5 kinds of isozyme, according to the sources, the organization of LD1 and LD2 mainly comes from heart, clinical commonly used alpha carboxyl butyric acid dehydrogenase (alpha HBD) is actually the sum of the activity of LD1 and LD2; LD3 mainly comes from the lungs and spleen. LD4 and LD5 (especially LD5) are mainly derived from the liver and skeletal muscle.

D - Lactic dehydrogenase activity mainly in myocardial infarction, acute or chronic hepatitis, liver cancer, particularly metastatic liver cancer, and other visible in skeletal muscle disease, blood system diseases, pulmonary infarction, hypothyroidism, nephrotic syndrome and late malignant tumor, etc.

 

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