Collagens polypeptide

Asia Bio-Pharmaceutical Research Institute

Collagens polypeptide

Product name:Collagens polypeptide
CAS:9007-34-5
Specification:1g
Description:
Product categories:Peptide;CollagenCell Signaling Enzymes;ECM ProteinsCytoskeleton and Extracellular Matrix;Extracellular Matrix;
                                  Extracellular Matrix Peptides and Proteins;Matrix Metalloproteinases Products;2DStem Cell Expansion.
Collagens polypeptide is a amphotericelectrolyte, which depends on two factors. First, Collagens polypeptide has many acidic or alkaline side groups; Secondly, Collagens polypeptide each peptide chain ends for alpha amino, carboxyl and alpha - all these groups have the ability to accept or give proton, these can be dissociated group in a specific pH range, dissociative produce positive or negative, in other words, as the medium pH Collagens polypeptide (with a lot of positive or negative ions. The PKI values of the side groups of the collagen peptide chain are slightly different from the PKI values of the side groups of its constituent amino acids, which are caused by the influence of adjacent charges in the protein molecules. Collagens polypeptide has an isoelectric point of 7.5 ~ 7.8, which is relatively alkaline, because Collagens polypeptide has more basic amino acids than acidic amino acids. Collagens polypeptide is a polymer compound with colloidal properties and a certain viscosity in aqueous solution. The viscosity is lowest at isoelectric point, and the lower the temperature, the higher the viscosity.

Collagens polypeptide is a medical biomaterial characterized by its low immunogenicity. Collagens polypeptide has three types of antigenic molecules. The first type is Collagens polypeptide chain with non-helix end peptide, the second type is Collagens polypeptide chain with three helix conformation, and the third type is a-chain helix sequence of amino acids. The second type of antigenic factors are found only in natural Collagens, the third type is found only in denatured Collagens polypeptide, and the first type is found in both natural and denatured Collagens polypeptide.

 

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