Product name:Carboxylase,phosphoenolpyruvate (phosphate)
CAS:9067-77-0
Specification:25u
Description:Carboxylase phosphoenolpyruvate is an irreversible enzyme that catalyzes phosphoenolpyruvate to oxaloacetic acid with carbon dioxide. It is widely found in plants and bacteria and is absent in animals and filamentous molds. It is found in plant chloroplasts and in soluble graded precipitates of bacteria. Tetramers with enzyme molecular weight of about 360,000 can be affected by many factors, such as acetyl-coa activation and aspartic acid inhibition. This enzyme is a allosteric enzyme whose main function is to supply oxaloacetic acid for the tricarboxylic acid cycle. In addition, it is also related to C4 plant photosynthetic carbon dioxide fixation reaction (C4 dicarboxylic acid cycle) and malic acid formation (sedum acid metabolism) of sedum plants.
Carboxylase phosphoenolpyruvate has a secondary structure of 52% alpha helix and no beta folding. The four subunits constituting the enzyme are combined in an isomorphic manner, and its four-level structure belongs to D2 symmetry, which may be arranged in a quasi-tetrahedron in space. The dissociation - polymerization of the enzyme subunit can regulate the enzyme activity. The different binding sites of different effectors indicate that the enzyme has the molecular characteristics of multiple regulatory sites.
Chemical property:Freeze-dried powder
Synonym: Phosphoenolpyruvate carboxylase (phosphate); Phosphoenolpyruviccarboxylase