Product name:Adenine
CAS:73-24-5
Molecular Formula:C5H5N5
Formula Weight:135.13
Specification:5g
Description:
Adenine is a white fine powder crystal with a strong salty taste. Insoluble in cold water, soluble in boiling water, acid and alkali, slightly soluble in ethanol, insoluble in ether and chloroform.
4, 6-dichloro-5-nitropyrimidine was aminated with ammonia water to 4, 6-diamino-5-nitropyrimidine, which was cyclized with formic acid, formyl ammonia and sodium thiosulfate. The process is as follows: 4, 6-dichloro-5-nitropyrimidine is dissolved in ethanol, heated to 75-78℃ for reflux 0.5h, ammonia is added, and the reflux is heated for 1.5h. After cooling and filtration, washing and drying, 4, 6-diamino-5-nitropyrimidine (ammonia) was obtained. Add formamide, water and ammonia to the reaction tank. Heat up to 100-130℃, add insurance powder in stages. Add finish, cool down to 100℃, add formic acid, then heat up to 170℃, hold for 2h. Vacuum distillation recovery solvent. After steaming, dissolve with hot water and decolorize with activated carbon twice. Adjust pH8-9 with ammonia water, cool, precipitate light yellow solid, filter, wash with water until no sulfate. You get Adenine. Adenine can also be recovered as a byproduct of glutamic acid fermentation. Industrial products are yellowish crystalline.