Product name:4-Methylumbelliferone
CAS:90-33-5
Molecular Formula:C10H8O3
Formula Weight:176.17
Specification:25g
Description:4-Methylumbelliferone is acicular crystallization. Melting point 185-186℃ (194-195℃) soluble in ethanol, acetic acid, alkali solution and ammonia, slightly soluble in hot water, ether and chloroform. Blue fluorescence with concentrated sulfuric acid.
4-Methylumbelliferone is obtained from resorcinol and acetoacetate through cyclization. The concentrated sulfuric acid was cooled to below 10℃, and the solution composed of resorcinol and ethyl acetoacetate was added under agitation, after which it was placed for 12h. Then the reactant is put into the water with broken ice, the precipitation is filtered out, and the product is refined with dilute sodium hydroxide solution and dilute sulfuric acid.
4-Methylumbelliferone is suitable for the standard of enzyme activity determination and laser dye. An indicator for the determination of nitric acid.
Chemical property:acicular crystal
Use:Serve as medicine intermediate.