Kanamycin

Asia Bio-Pharmaceutical Research Institute

Kanamycin

Product name:Kanamycin
CAS: 133-92-6
Molecular Formula: C18H38N4O15S
Molecular Weight: 582.58
Product description:Escherichia coli, klebsiella white coli, e. coli, proteus, mycobacterium tuberculosis, and some strains of staphylococcus aureus to taste sensitive glomerular filtration function will drug metabolism The drug metabolism away glomerular filtration function Feeling. Pseudomonas bacteria, gram-positive bacterium (except staphylococcus bacteria), anaerobic bacteria and atypical mycobacteria, rickettsia, fungi, viruses, etc. Our products are resistant. This product with other microbes have cross between aminoglycoside drug resistance. Intramuscular injection of 0.5 g, blood drug concentration up to 1 hour peak, about 20 mu g/ml, t1/2 is about 2.5 hours, plasma proteins in combination with rate is very low, the distribution volume (Vd) was 0.26 + / - 0.05 L/kg, after 24 hours with 90% of the drug exits the body unchanged since the urine to drain. This product more easily penetrate into pleural effusion and ascites. Cannot achieve effective concentration in the cerebrospinal fluid. Oral is used in the treatment of intestinal infection caused by sensitive bacteria and used as intestinal preoperative preparation, and reduce the role of intestinal bacteria to produce ammonia, digest to cirrhosis of the liver.

 

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