Product name:Fasudil
CAS: 103745-39-7
Molecular Formula: C14H17N3O2S
Molecular Weight: 291.37
Product description:This product is a white, white or light yellow crystalline powder. Odourless and slightly bitter taste. Have led to wet. This product is easily dissolved in water, dissolved in methanol, slightly soluble in ethanol, slightly soluble in chloroform, hardly soluble in ether.A protein kinase inhibitor or intracellular calcium antagonists. Vascular smooth muscle contraction is due to the smooth muscle cells Ca2 + concentration significantly increased activation of key enzyme. When the CA2 + reaches a certain concentration, combined with CA2 + binding protein calmodulin, activate the myosin light chain phosphorylase, the myosin light chain phosphorylation, cause muscle contractions. Subarachnoid hemorrhage, the blood vessels in the release of all kinds of vasoconstrictor substance involved in vascular spasm, ultimately through the phosphorylation of myosin light chain cause vasoconstriction. Hydrochloric acid method of shu, the final stage of the process by blocking vasoconstriction, phosphorylation of myosin light chain to dilate blood vessels, inhibit vasospasm.