Cyloserine

Asia Bio-Pharmaceutical Research Institute

Cyloserine

Product name:Cyloserine
CAS:339-72-0
Molecular Formula: C3H6N2O2
Molecular Weight: 102.09
Product description:White or reddish crystals or powder. Has the water absorbability. Easy deliquescence. Taste slightly acidic. Melting point of 155 ~ 156 ℃ (decomposition), than the polarimetric + 115 ° (c = 1, water, 22 ℃) and + 137 ° c (naoh) = 5, 2 mol / 1. Soluble in water, soluble in ethanol, slightly soluble in chloroform, ether, insoluble in general organic solvents. In alkaline solution is relatively stable, quickly decompose in acidic and neutral solution.Broad-spectrum antimicrobial agents, for many gram-positive bacterium and negative bacteria have weaker antibacterial effect. Has inhibitory effect on bacteria, fight n/med tuberculosis bacili effect is much weaker than isoniazid, streptomycin, its antibacterial mechanism is to interfere with the synthesis of bacterial cell walls, the concentration of n/med tuberculosis bacili resistance for 5 ~ 20 mg/L, no cross resistance with other anti-tb drugs, bacteria of not easy the creation bears the medicine. As a result of the nervous system toxicity is bigger, only for other drug treatment is invalid.

 

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