Sodium gluconate synthesis method: In the industry, glucose-containing substances (such as grains) are generally used as raw materials, and gluconic acid is first prepared from glucose by fermentation, and then neutralized by sodium hydroxide to obtain Sodium gluconate. Electrolysis and oxidation synthesis. Most of China uses chemical oxidation-secondary bromination to produce and synthesize.
Depending on the type of fermentation enzyme used, the fermentation process can be divided into two clocks, one using the enzyme of Aspergillus Niger and the other, the latter being dehydrogenated to form lactone by means of glucose, followed by decomposition of the ester.
Sodium gluconate can also be obtained directly from glucose fermentation. At this time, the composition of the fermentation base may be: glucose 250-350 g/L, magnesium sulfate heptahydrate 0.2-0.3 g/L, diammonium hydrogen phosphate or urea 0.4-0.5 g/L. This substrate must be sterilized. During the fermentation process, the temperature is controlled to 30-32 degrees, the pH is controlled to 5.5-6.5 by 30%~50% sodium hydroxide, and the fermentation process lasts 40~100h. Then, the microorganisms are removed by filtration and washing, the activated carbon is decolored, and then filtered, concentrated, or spray dried to obtain a finished product.
Sodium gluconate synthesis method
