1. Disodium phosphonomycin has a wide antibacterial spectrum, high bioavailability, fast absorption, strong antibacterial activity and is not affected by diet. It has a killing effect on Gram-positive bacteria and negative bacteria, especially for Pseudomonas aeruginosa, Proteus, Salmonella and Staphylococcus and Escherichia coli which are resistant to various drugs. It is used in animals, has no drug resistance and cross-resistance, and has good clinical treatment effect.
2. Disodium phosphonomycin is rapidly sterilized: This product is a fast bactericide, and its effect is obvious after 1-2 hours. About 25% of E. coli was killed 1 hour after exposure to fosfomycin (12.5 μg/ml) and all died within 4-6 hours. Pseudomonas aeruginosa and Staphylococcus aureus were also killed at 4 and 8 hours, respectively.
3. Disodium phosphonomycin has low toxic and side effects, is less irritating to the body, does not have acute toxicity and adverse reactions, and does not increase the burden on the kidneys.
4. Low Residue: The elimination time to reach the residue standard in muscles and organs is 48-72 hours.
Pharmacological action of Disodium phosphonomycin
