Existing research reports indicate that folic acid plays an extremely important role in human health. Folic acid deficiency can lead to neonatal neurological abnormalities, thromboembolic heart, cerebrovascular disease, anorexia and anorexia nervosa, megaloblastic anemia, senile vascular dementia, depression and other diseases.
(1) Investigation of the effect of folic acid on neonatal neural tube defects
Some scholars have studied the supplementation of folic acid from diets and nutraceuticals in the United States in 2003-2006. The folic acid intake of women of childbearing age must be improved. In high-risk areas of NTDs, the daily supply of folic acid to pregnant women is only 100ug, which is much lower than the daily requirement of pregnant women.
In a survey of the effects of folic acid intake on blood folic acid levels in lactating women in Canada, it was concluded that lactating women should consume 400 ug of folic acid per day. Folic acid plays an important role in regulating neurogenesis and programmed cell death.
Intensive supplementation of folic acid in US foods reduced the birth rate of infants with nerve closure defects by 19%, but did not rule out the effects of other factors on this reduction.
(2) Study on the effect of folic acid on other human diseases
In addition to its incomplete effect on preventing nerve closure in infants, folic acid also plays a role in the prevention of some common diseases in humans.