Product name:loperamide hydrochloride
CAS: 34552-83-5
Molecular Formula: C29H34Cl2N2O2
Molecular Weight: 513.4985
Product description:A white or white crystalline powder, can make a laxative, or diarrhea long-acting antibacterial drugs, used in the treatment of acute and chronic diarrhea. Overdose, may appear sleepiness, constipation, muscle tension, miosis, breathing slow poisoning symptoms, such as available naloxone detoxification, and observation of the patients for at least 48 hours, in order to discover the inhibition of the central nervous system.Acting on the intestinal wall of opioid receptors, prevent the release of acetylcholine and prostaglandin, thus inhibiting intestinal peristalsis, extend the residence time of intestinal contents. Can increase the tension of anal sphincter, therefore inhibits fecal incontinence and urgent, also can be used in the anorectal surgery patients. The high binding affinity and the colon wall and obvious 'metabolism', makes it almost not into the whole body blood circulation.