1. The effect of drugs on pregnancy: Oxytetracycline can enter the fetus through the blood-placental barrier and deposit in the calcium regions of teeth and bones, causing discoloration of fetal teeth, poor regeneration of enamel and inhibition of fetal bone growth. Therefore, pregnant women should not use oxytetracycline.
2. The effect of drugs on breastfeeding: oxytetracycline can be secreted by milk, and the concentration in milk is higher. Although oxytetracycline can form an insoluble complex with calcium in milk, absorption is rare, but it can be caused by such drugs. Permanent discoloration of the teeth, enamel dysplasia and inhibition of the development of the baby's bones, so lactating women must weigh the pros and cons to decide whether to use.
3. The effect of the drug on the test value or diagnosis: (1) When the concentration of urinyl phthalate (Hingerty method) is measured, the measurement result may be high due to the interference of oxytetracycline on fluorescence; (2) the administration of a small number of patients Alkaline phosphatase, blood urea nitrogen, serum amylase, serum bilirubin, and serum aminotransferase may be increased.
4. Before and after medication and medication should be checked or monitored: (1) liver and kidney function should be checked regularly during medication; (2) those who take longer treatment with oxytetracycline should measure blood concentration if necessary.
Use oxytetracycline precautions
